Transcatheter closure of patent ductus arteriosus in adults using the Amplatzer duct occluder: Initial results and follow-up

Thomas Hong, William E. Hellenbrand, Ziyad M. Hijazi

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Background: Surgical closure of patent ductus arteriosus in adult patients may be problematic. Transcatheter closure of patent ductus arteriosus is an established procedure. Recently, transcatheter closure of patent ductus arteriosus using the Amplatzer duct occluder has been shown to be safe and efficacious. We present our experience with this device in adults. Methods and Results: Between January 2000 and January 2002, 41 adult patients (31 females and 10 males) with a patent ductus arteriosus were referred for closure with the Amplatzer duct occluder. The median age was 35.6 years (range 18-70.7 years) and the median weight was 65.8 kg (range 32.7-164.5 kg). Of these 41 patients, 37 underwent attempted closure of the patent ductus arteriosus using the Amplatzer duct occluder. The device was successfully deployed in all patients except 1. Complete angiographic closure was seen immediately after device deployment in 29 out of 36 patients (81%). Complete echocardiographic closure was demonstrated within 24 hours post-procedure in 34 out of 36 patients (94%), and at 6-month follow-up in 35 out of 36 patients (97%). No complications related to device implantation occurred in any patient. Conclusions: Closure of patent ductus arteriosus using the Amplatzer duct occluder is safe and effective in adults.

Original languageEnglish (US)
Pages (from-to)384-389
Number of pages6
JournalIndian Heart Journal
Volume54
Issue number4
StatePublished - Jul 1 2002

Keywords

  • Amplatzer duct occluder
  • Patent ductus arteriosus
  • Transcatheter closure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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