Transcatheter closure of large atrial septal defects in 18 patients

Zhanjun Guan, Yongwen Qin, Xianxian Zhao, Jijun Ding, Xing Zheng, Vince Nguyen

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Purpose: This study was designed to evaluate the efficacy and safety of transcatheter closure of large atrial septal defects (ASD). Methods: Eighteen patients diagnosed as ostium secundum defect with a diameter of 30-40 mm were enrolled in this study. With the guidance of echocardiography and fluoroscopy, the Amplazter occlusion devices were implanted percutaneously through the femoral vein. Results: A small residual left-to-right shunt was detected with echocardiography immediately postprocedure but resolved after 1 week. The occlusion devices remained in proper position, and there was no residual shunt at 1- and 29-month follow-ups. Cardiac function and atrial sizes improved significantly as compared with the preclosure states. Conclusions: Transcatheter closure of large atrial septal defects with the Amplazter occlusion device is feasible, safe and effective.

Original languageEnglish (US)
Pages (from-to)24-27
Number of pages4
JournalClinical Cardiology
Volume31
Issue number1
DOIs
StatePublished - Jan 2008

Keywords

  • Atrial septal defect
  • Occlusion device
  • Transcatheter occlusion

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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