Transcatheter Aortic Valve-in-Valve Procedure in Patients with Bioprosthetic Structural Valve Deterioration

Ross M. Reul, Mahesh K. Ramchandani, Michael J. Reardon

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations


Surgical aortic valve replacement is the gold standard procedure to treat patients with severe, symptomatic aortic valve stenosis or insufficiency. Bioprosthetic valves are used for surgical aortic valve replacement with a much greater prevalence than mechanical valves. However, bioprosthetic valves may fail over time because of structural valve deterioration; this often requires intervention due to severe bioprosthetic valve stenosis or regurgitation or a combination of both. In select patients, transcatheter aortic valve replacement is an alternative to surgical aortic valve replacement. Transcatheter valve-in-valve (ViV) replacement is performed by implanting a transcatheter heart valve within a failing bioprosthetic valve. The transcatheter ViV operation is a less invasive procedure compared with reoperative surgical aortic valve replacement, but it has been associated with specific complications and requires extensive preoperative work-up and planning by the heart team. Data from experimental studies and analyses of results from clinical procedures have led to strategies to improve outcomes of these procedures. The type, size, and implant position of the transcatheter valve can be optimized for individual patients with knowledge of detailed dimensions of the surgical valve and radiographic and echocardiographic measurements of the patient's anatomy. Understanding the complexities of the ViV procedure can lead surgeons to make choices during the original surgical valve implantation that can make a future ViV operation more technically feasible years before it is required.

Original languageEnglish (US)
Pages (from-to)132-141
Number of pages10
JournalMethodist DeBakey cardiovascular journal
Issue number3
StatePublished - Jul 1 2017


  • SAVR
  • TAVR
  • bioprosthetic valves
  • surgical aortic valve replacement
  • transcatheter aortic valve replacement
  • valve-in-valve repair

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Transcatheter Aortic Valve-in-Valve Procedure in Patients with Bioprosthetic Structural Valve Deterioration'. Together they form a unique fingerprint.

Cite this