TY - JOUR
T1 - Transcatheter aortic valve implantation in a patient with unicuspid aortic valve
AU - Nascimbene, Angelo
AU - Loyalka, Pranav
AU - Gregoric, Igor D.
AU - Bellera, Ricardo
AU - Malahfji, Maan
AU - Petrovic, Marija
AU - Kar, Biswajit
N1 - Publisher Copyright:
© 2017 by the Texas Heart ® Institute, Houston.
PY - 2017/4
Y1 - 2017/4
N2 - Transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valves has been successfully performed, but there is a lack of published experience in percutaneous treatment of patients with unicuspid valves and severe aortic stenosis. We describe a case of TAVR in such a patient. A 31-year-old woman with Turner syndrome—who had undergone coarctation repair via subclavian flap at age 7 days and an aortic valvotomy at age 6 weeks—presented with severe symptomatic aortic stenosis. She was deemed inoperable because of her severe pulmonary hypertension and numerous comorbidities; consequently, a 20-mm Edwards SApIEN 3 Transcatheter Heart Valve was offered for compassionate use. Postdeployment angiography and transesophageal echocardiography and aortography revealed no aortic insufficiency. Transcatheter aortic valve replacement for unicuspid aortic valve stenosis is technically feasible. Before implantation, particular attention should be paid to the interplay between the large single leaflet, coronary ostia, and stented valve, to select the correct size and position of the device. Some degree of intraoperative aortic migration should be anticipated.
AB - Transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valves has been successfully performed, but there is a lack of published experience in percutaneous treatment of patients with unicuspid valves and severe aortic stenosis. We describe a case of TAVR in such a patient. A 31-year-old woman with Turner syndrome—who had undergone coarctation repair via subclavian flap at age 7 days and an aortic valvotomy at age 6 weeks—presented with severe symptomatic aortic stenosis. She was deemed inoperable because of her severe pulmonary hypertension and numerous comorbidities; consequently, a 20-mm Edwards SApIEN 3 Transcatheter Heart Valve was offered for compassionate use. Postdeployment angiography and transesophageal echocardiography and aortography revealed no aortic insufficiency. Transcatheter aortic valve replacement for unicuspid aortic valve stenosis is technically feasible. Before implantation, particular attention should be paid to the interplay between the large single leaflet, coronary ostia, and stented valve, to select the correct size and position of the device. Some degree of intraoperative aortic migration should be anticipated.
KW - Aortic valve stenosis/therapy
KW - Aortic valve/abnormalities/pathology
KW - Cardiac catheterization/instrumentation
KW - Congenital/complications
KW - Heart defects
KW - Heart valve diseases
KW - Heart valve prosthesis implantation/methods
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UR - http://www.scopus.com/inward/citedby.url?scp=85018328731&partnerID=8YFLogxK
U2 - 10.14503/THIJ-15-5602
DO - 10.14503/THIJ-15-5602
M3 - Article
C2 - 28461798
AN - SCOPUS:85018328731
SN - 0730-2347
VL - 44
SP - 127
EP - 130
JO - Texas Heart Institute Journal
JF - Texas Heart Institute Journal
IS - 2
ER -