Tracking methicillin-resistant Staphylococcus aureus clones in Colombian hospitals over 7 years (1996-2003): Emergence of a new dominant clone

César Cruz, Jaime Moreno, Adriana Renzoni, Marilyn Hidalgo, Jinnethe Reyes, Jacques Schrenzel, Daniel Lew, Elizabeth Castañeda, César A. Arias

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

Worldwide dissemination of methicillin-resistant Staphylococcus aureus (MRSA) clones is a well-characterised phenomenon. Two hundred isolates of MRSA recovered from 17 Colombian hospitals collected between 2001 and 2003 were characterised by pulsed-field gel electrophoresis (PFGE). A new dominant electrophoretic pattern unrelated to previously characterised clones in Colombia was detected in 137 (68.5%) of these isolates. Only 40 (20%) isolates still showed a pattern closely related to a previously described dominant clone. The new electrophoretic pattern was indistinguishable from a cluster of isolates recovered in Chile between 1996 and 1998. Isolates from this clonal cluster exhibited multidrug resistance but were susceptible to linezolid and glycopeptides. The results indicate a shift in the population genetics of Colombian MRSA and confirm dissemination of the Chilean clone for the first time.

Original languageEnglish (US)
Pages (from-to)457-462
Number of pages6
JournalInternational Journal of Antimicrobial Agents
Volume26
Issue number6
DOIs
StatePublished - Dec 2005

Keywords

  • Antibiotic resistance
  • Methicillin-resistant Staphylococcus aureus
  • Molecular epidemiology

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)

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