TRACE METALS AND DEGENERATIVE DISEASES OF THE SKELETON

J. Savory, Roger L. Bertholf, M. R. Wills

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Abstract Aluminum related osteodystrophy is the most important manifestion of trace metal toxicity related to degenerative diseases of the skeleton. Aluminum overload occurs in chronic renal failure patients on hemodialysis treatment and results from transfer from dialysis solutions and from oral intake of aluminum containing phosphate binding gels. Laboratory diagnosis involves serum and bone analysis and bone staining for aluminum. A challenge test with desferoxamine also aids in the diagnosis. Electrothermal atomic absorption spectrometry is widely used for aluminum detection. Guidelines for toxic concentrations of aluminum have been established. 1986 Nordic Pharmacological Society

Original languageEnglish (US)
Pages (from-to)282-288
Number of pages7
JournalActa Pharmacologica et Toxicologica
Volume59
DOIs
StatePublished - Jan 1 1986

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology

Fingerprint Dive into the research topics of 'TRACE METALS AND DEGENERATIVE DISEASES OF THE SKELETON'. Together they form a unique fingerprint.

Cite this