Abstract
Abstract Aluminum related osteodystrophy is the most important manifestion of trace metal toxicity related to degenerative diseases of the skeleton. Aluminum overload occurs in chronic renal failure patients on hemodialysis treatment and results from transfer from dialysis solutions and from oral intake of aluminum containing phosphate binding gels. Laboratory diagnosis involves serum and bone analysis and bone staining for aluminum. A challenge test with desferoxamine also aids in the diagnosis. Electrothermal atomic absorption spectrometry is widely used for aluminum detection. Guidelines for toxic concentrations of aluminum have been established. 1986 Nordic Pharmacological Society
Original language | English (US) |
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Pages (from-to) | 282-288 |
Number of pages | 7 |
Journal | Acta Pharmacologica et Toxicologica |
Volume | 59 |
DOIs | |
State | Published - Dec 1986 |
ASJC Scopus subject areas
- Toxicology
- Pharmacology