Toxoplasmosis Neuroretinitis

Richard H. Fish, John C. Hoskins, Lanning B. Kline

Research output: Contribution to journalArticlepeer-review

59 Scopus citations


Background: Neuroretinitis is a distinct clinical entity consisting of moderate to severe visual loss, optic nerve head edema, macular exudate in a stellate pattern, and variable vitreous inflammation. Although the etiology is usually postviral or idiopathic, an acute infectious cause occasionally is demonstrated. Methods: Five juvenile or young adult patients with neuroretinitis are presented with serologic evidence of Toxoplasma gondii infection. Four of the five patients were treated with systemic antibiotics and corticosteroids; one patient was not treated. Results: With a mean follow-up period of 50 months, visual acuity returned to 20/25 or better in four patients, with one patient regaining visual acuity of 20/60. Two patients had one or more recurrent episodes of neuroretinitis, distinguishing toxoplasmosis from idiopathic neuroretinitis, which is usually a monophasic illness. Conclusion: Toxoplasmosis infection is a rare, but potentially treatable, form of neuroretinitis and should be included in the differential diagnosis of 'Leber's idiopathic stellate retinopathy.'

Original languageEnglish (US)
Pages (from-to)1177-1182
Number of pages6
Issue number8
StatePublished - 1993

ASJC Scopus subject areas

  • Ophthalmology


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