TY - JOUR
T1 - Toxoplasmosis Neuroretinitis
AU - Fish, Richard H.
AU - Hoskins, John C.
AU - Kline, Lanning B.
N1 - Funding Information:
Originally received: October 26, 1992. Revision accepted: February 12, 1993. 1 Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas. 2 Retina Associates of Knoxville, Knoxville. 3 Department of Ophthalmology, University of Alabama Birmingham Eye Foundation Hospital, Birmingham. Dr. Fish is currently affiliated with Vitreoretinal Consultants, Houston. Presented in part as a poster at the American Academy of Ophthalmology Annual Meeting, New Orleans, October 1989. Supported in part by an unrestricted grant from Research to Prevent Blindness, Inc, New York, New York. Reprint requests to Richard H. Fish, MD, Vitreoretinal Consultants, 1200 Binz, Suite 1290, Houston, TX 77004.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1993
Y1 - 1993
N2 - Background: Neuroretinitis is a distinct clinical entity consisting of moderate to severe visual loss, optic nerve head edema, macular exudate in a stellate pattern, and variable vitreous inflammation. Although the etiology is usually postviral or idiopathic, an acute infectious cause occasionally is demonstrated. Methods: Five juvenile or young adult patients with neuroretinitis are presented with serologic evidence of Toxoplasma gondii infection. Four of the five patients were treated with systemic antibiotics and corticosteroids; one patient was not treated. Results: With a mean follow-up period of 50 months, visual acuity returned to 20/25 or better in four patients, with one patient regaining visual acuity of 20/60. Two patients had one or more recurrent episodes of neuroretinitis, distinguishing toxoplasmosis from idiopathic neuroretinitis, which is usually a monophasic illness. Conclusion: Toxoplasmosis infection is a rare, but potentially treatable, form of neuroretinitis and should be included in the differential diagnosis of 'Leber's idiopathic stellate retinopathy.'
AB - Background: Neuroretinitis is a distinct clinical entity consisting of moderate to severe visual loss, optic nerve head edema, macular exudate in a stellate pattern, and variable vitreous inflammation. Although the etiology is usually postviral or idiopathic, an acute infectious cause occasionally is demonstrated. Methods: Five juvenile or young adult patients with neuroretinitis are presented with serologic evidence of Toxoplasma gondii infection. Four of the five patients were treated with systemic antibiotics and corticosteroids; one patient was not treated. Results: With a mean follow-up period of 50 months, visual acuity returned to 20/25 or better in four patients, with one patient regaining visual acuity of 20/60. Two patients had one or more recurrent episodes of neuroretinitis, distinguishing toxoplasmosis from idiopathic neuroretinitis, which is usually a monophasic illness. Conclusion: Toxoplasmosis infection is a rare, but potentially treatable, form of neuroretinitis and should be included in the differential diagnosis of 'Leber's idiopathic stellate retinopathy.'
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U2 - 10.1016/S0161-6420(13)31511-5
DO - 10.1016/S0161-6420(13)31511-5
M3 - Article
C2 - 8341498
AN - SCOPUS:0027280049
VL - 100
SP - 1177
EP - 1182
JO - Ophthalmology
JF - Ophthalmology
SN - 0161-6420
IS - 8
ER -