Total synthesis of argyrins A and e

Wenbin Wu, Zheng Li, Guangbiao Zhou, Sheng Jiang

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


The total synthesis of argyrins A and E were accomplished using a convergent strategy by condensation of one tripeptide and two dipeptide fragments. The synthesis strategy, which was developed for the protection of peptide fragments and identification of the optimum macrocylization site, can be applied to further synthetic studies involving other members of the argyrin family.

Original languageEnglish (US)
Pages (from-to)2488-2491
Number of pages4
JournalTetrahedron Letters
Issue number19
StatePublished - May 11 2011

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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