Total synthesis of argyrins A and e

Wenbin Wu; Zheng Li; Guangbiao Zhou; Sheng Jiang

doi:10.1016/j.tetlet.2011.03.021

Total synthesis of argyrins A and e

Wenbin Wu, Zheng Li, Guangbiao Zhou, Sheng Jiang

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Abstract

The total synthesis of argyrins A and E were accomplished using a convergent strategy by condensation of one tripeptide and two dipeptide fragments. The synthesis strategy, which was developed for the protection of peptide fragments and identification of the optimum macrocylization site, can be applied to further synthetic studies involving other members of the argyrin family.

Original language	English (US)
Pages (from-to)	2488-2491
Number of pages	4
Journal	Tetrahedron Letters
Volume	52
Issue number	19
DOIs	https://doi.org/10.1016/j.tetlet.2011.03.021
State	Published - May 11 2011

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2011.03.021

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title = "Total synthesis of argyrins A and e",

abstract = "The total synthesis of argyrins A and E were accomplished using a convergent strategy by condensation of one tripeptide and two dipeptide fragments. The synthesis strategy, which was developed for the protection of peptide fragments and identification of the optimum macrocylization site, can be applied to further synthetic studies involving other members of the argyrin family.",

author = "Wenbin Wu and Zheng Li and Guangbiao Zhou and Sheng Jiang",

year = "2011",

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doi = "10.1016/j.tetlet.2011.03.021",

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T1 - Total synthesis of argyrins A and e

AU - Wu, Wenbin

AU - Li, Zheng

AU - Zhou, Guangbiao

AU - Jiang, Sheng

PY - 2011/5/11

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N2 - The total synthesis of argyrins A and E were accomplished using a convergent strategy by condensation of one tripeptide and two dipeptide fragments. The synthesis strategy, which was developed for the protection of peptide fragments and identification of the optimum macrocylization site, can be applied to further synthetic studies involving other members of the argyrin family.

AB - The total synthesis of argyrins A and E were accomplished using a convergent strategy by condensation of one tripeptide and two dipeptide fragments. The synthesis strategy, which was developed for the protection of peptide fragments and identification of the optimum macrocylization site, can be applied to further synthetic studies involving other members of the argyrin family.

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DO - 10.1016/j.tetlet.2011.03.021

M3 - Article

AN - SCOPUS:79953722203

SN - 0040-4039

VL - 52

SP - 2488

EP - 2491

JO - Tetrahedron Letters

JF - Tetrahedron Letters

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ER -

Total synthesis of argyrins A and e

Abstract

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