Tissue plasminogen activator in the surgical excision of subfoveal choroidal neovascular membranes

J. W. Thomas, P. F. Lopez, H. M. Lambert

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

We investigated the use of tissue plasminogen activator (t-PA) as an adjunct to the surgical removal of subfoveal choroidal neovascular membranes. t-PA in a concentration of 6 μg/0.1 cc dissolved the fibrin rim surrounding recent subfoveal membranes but was less effective on more mature lesions. t-PA may be a useful intraoperative tool to limit the damage to surrounding structures during the surgical excision of recent subfoveal choroidal neovascular membranes with surrounding fibrin rims.

Original languageEnglish (US)
Pages (from-to)374-376
Number of pages3
JournalOphthalmic Surgery
Volume26
Issue number4
StatePublished - Jan 1 1995

ASJC Scopus subject areas

  • Ophthalmology

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