Tissue Engineering: Biomimetic Concealing of PLGA Microspheres in a 3D Scaffold to Prevent Macrophage Uptake (Small 11/2016)

Silvia Minardi, Bruna Corradetti, Francesca Taraballi, Monica Sandri, Jonathan O Martinez, Sebastian T Powell, Anna Tampieri, Bradley K Weiner, Ennio Tasciotti

Research output: Contribution to journalArticle

Abstract

Avoiding the clearance of drug delivery systems from 3D scaffolds is crucial to preserve the bioactivity of their therapeutic payload. This is accomplished on page 1479, by E. Tasciotti and co-workers, through a "concealing" strategy: cloaking PLGA microspheres with the type I collagen matrix of a biomimetic scaffold, which enables the control of the production of inflammatory mediators.

Original languageEnglish (US)
Pages (from-to)1394
JournalSmall (Weinheim an der Bergstrasse, Germany)
Volume12
Issue number11
DOIs
StatePublished - Mar 2016

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