Tissue-cultured smooth muscle cells from normal and atherosclerotic arteries

S. G. Eskin, H. D. Sybers, L. T. Navarro, Antonio Gotto, M. E. DeBakey

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

One hypothesis put forth to explain atherogenesis is that the lesions originate with neoplastically transformed smooth muscle cells (SMC) in the vessel wall. If this is so, SMC derived from lesions may exhibit transformed behavior in tissue culture, for example, a capacity to replicate infinitely and a rapid rate of proliferation compared to cells derived from uninvolved vessel wall.

Original languageEnglish
Title of host publicationCardiovascular Research Center Bulletin
Pages85-89
Number of pages5
Volume18
Edition4
StatePublished - Dec 1 1980

ASJC Scopus subject areas

  • Medicine(all)

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