Time-resolved three-dimensional contrast-enhanced magnetic resonance angiography in patients with chronic expanding and stable aortic dissections

Michael Trojan, Fabian Rengier, Drosos Kotelis, Matthias Müller-Eschner, Sasan Partovi, Christian Fink, Christof Karmonik, Dittmar Böckler, Hans Ulrich Kauczor, Hendrik Von Tengg-Kobligk

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Objective. To prospectively evaluate our hypothesis that three-dimensional time-resolved contrast-enhanced magnetic resonance angiography (TR-MRA) is able to detect hemodynamic alterations in patients with chronic expanding aortic dissection compared to stable aortic dissections. Materials and Methods. 20 patients with chronic or residual aortic dissection in the descending aorta and patent false lumen underwent TR-MRA of the aorta at 1.5 T and repeated follow-up imaging (mean follow-up 5.4 years). 7 patients showed chronic aortic expansion and 13 patients had stable aortic diameters. Regions of interest were placed in the nondissected ascending aorta and the false lumen of the descending aorta at the level of the diaphragm (FL-diaphragm level) resulting in respective time-intensity curves. Results. For the FL-diaphragm level, time-to-peak intensity and full width at half maximum were significantly shorter in the expansion group compared to the stable group (p=0.027 and p=0.003), and upward and downward slopes of time-intensity curves were significantly steeper (p=0.015 and p=0.005). The delay of peak intensity in the FL-diaphragm level compared to the nondissected ascending aorta was significantly shorter in the expansion group compared to the stable group (p=0.01). Conclusions. 3D TR-MRA detects significant alterations of hemodynamics within the patent false lumen of chronic expanding aortic dissections compared to stable aortic dissections.

Original languageEnglish (US)
Article number5428914
JournalContrast Media and Molecular Imaging
Volume2017
DOIs
StatePublished - 2017

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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