Thin endometrium after radiation therapy as an unresolved treatment challenge: a case report

Rashmi Kudesia, Satu Kuokkanen

Research output: Contribution to journalArticle

Abstract

Receptive endometrium is essential for successful implantation and ongoing pregnancy. Significant health issues and associated therapies, especially oncologic therapies, have potential to negatively impact future fertility in young women. Irradiation and chemotherapeutic alkylating agents are known to cause ovarian failure in most females; however, less well is characterized the impact of irradiation on uterine development and integrity. With an increasing number of cancer survivors, women are seeking infertility treatment after such therapies. Here, we present a young woman who developed ovarian failure after the treatment of acute myeloid leukemia with bone marrow transplant and preceding irradiation and chemotherapy and who was diagnosed with thin endometrial lining while seeking infertility therapy.

Original languageEnglish (US)
Pages (from-to)701-703
Number of pages3
JournalGynecological Endocrinology
Volume32
Issue number9
DOIs
StatePublished - 2016

Keywords

  • Oncologic treatment
  • radiation therapy
  • thin endometrium
  • uterus

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Obstetrics and Gynecology

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