Abstract
After myocardial injury, the cardiac muscle does not regenerate and heals by forming a scar. This process results in loss of heart function and ultimately heart failure. Recent application of reprogramming technology, where forced expression of master regulators convert scar-forming cells to become cardiovascular cells in vivo, has fueled new hope for the development of therapies targeting heart disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 210-212 |
| Number of pages | 3 |
| Journal | Methodist DeBakey cardiovascular journal |
| Volume | 9 |
| Issue number | 4 |
| DOIs | |
| State | Published - 2013 |
Keywords
- cardiomyocytes
- cardiovascular diseases
- cardiovascular regeneration
- transdifferentiation
- transflammation
ASJC Scopus subject areas
- General Medicine
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