Therapeutic cloning applications for organ transplantation

Chester J. Koh, Anthony Atala

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


A severe shortage of donor organs available for transplantation in the United States leaves patients suffering from diseased and injured organs with few treatment options. Scientists in the field of tissue engineering apply the principles of cell transplantation, material science, and engineering to construct biological substitutes that will restore and maintain normal function in diseased and injured tissues. Therapeutic cloning, where the nucleus from a donor cell is transferred into an enucleated oocyte in order to extract pluripotent embryonic stem cells, offers a potentially limitless source of cells for tissue engineering applications. The present chapter reviews recent advances that have occurred in therapeutic cloning and tissue engineering and describes applications of these new technologies that may offer novel therapies for patients with end-stage organ failure.

Original languageEnglish (US)
Pages (from-to)193-201
Number of pages9
JournalTransplant Immunology
Issue number3-4
StatePublished - Apr 2004


  • Embryonic stem cells
  • Kidney
  • Regenerative medicine
  • Therapeutic cloning
  • Tissue engineering
  • Transplantation

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Transplantation


Dive into the research topics of 'Therapeutic cloning applications for organ transplantation'. Together they form a unique fingerprint.

Cite this