Therapeutic applications of low-toxicity spherical nanocarbon materials

Jing Wang, Zhongbo Hu, Jianxun Xu, Yuliang Zhao

Research output: Contribution to journalReview articlepeer-review

47 Scopus citations

Abstract

Nanocarbon materials have received considerable attention due to their unique structure and properties, which make them promising candidate materials for use in biomedical applications. In this review, we discuss the therapeutic applications of spherical nanocarbon materials, including fullerene nanoparticles, carbon nanohorn aggregates, nanodiamonds and porous carbon nanospheres, and their toxicology in biological systems. We put special emphasis on the antitumor effects of these multifunctional nanoparticles, which operate via novel mechanisms in a highly efficient manner. The low toxicities of these spherical nanocarbon materials as well as the possible effects of shape on toxicity are discussed.

Original languageEnglish (US)
Article number79
JournalNPG Asia Materials
Volume6
Issue number2
DOIs
StatePublished - Feb 2014

Keywords

  • Carbon nanohorns
  • Fullerenes
  • Nanodiamonds
  • Nanotherapy
  • Nanotoxicology

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Modeling and Simulation

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