Abstract
The STE2 gene of the yeast Saccharomyces cerevisiae encodes a component of the receptor for the oligopeptide pheromone α-factor (1). We have cloned and determined the nucleotide sequence of the STE2 gene. A sequence involved in the control of cell-type expression of the STE2 gene (2,3) was found 5′ of an open reading frame that could encode a protein of 431 amino acids. The predicted STE2 protein contains seven hydrophobic segments, suggesting that the α-factor receptor is an integral membrane protein. No extensive homology at the primary sequence level was detected between the predicted STE2 protein and other available protein sequences.
Original language | English (US) |
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Pages (from-to) | 8463-8475 |
Number of pages | 13 |
Journal | Nucleic Acids Research |
Volume | 13 |
Issue number | 23 |
DOIs | |
State | Published - Dec 9 1985 |
ASJC Scopus subject areas
- Genetics