TY - JOUR
T1 - The Vulnerable Plaque
T2 - Recent Advances in Computed Tomography Imaging to Identify the Vulnerable Patient
AU - Beg, Faheemullah
AU - Rehman, Hasan
AU - Al-Mallah, Mouaz H.
N1 - Publisher Copyright:
© 2020, Springer Science+Business Media, LLC, part of Springer Nature.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/10/1
Y1 - 2020/10/1
N2 - Purpose of Review: This review aims to summarize the role of coronary computed tomography plaque analysis in identifying high-risk patients and plaques. Recent Findings: In this review, we will describe the histopathological features of a vulnerable plaque as well as the coronary computed tomography characteristics including spotty calcification, low-attenuation fatty core, positive remodeling, and thin fibrous cap. We will also review several studies that assessed features of a vulnerable plaque on non-invasive imaging and evaluated them as risk predictors of future acute coronary events. Summary: Multiple recent studies suggested that coronary computed tomography angiography can accurately identify high-risk features of plaque that will predict future events.
AB - Purpose of Review: This review aims to summarize the role of coronary computed tomography plaque analysis in identifying high-risk patients and plaques. Recent Findings: In this review, we will describe the histopathological features of a vulnerable plaque as well as the coronary computed tomography characteristics including spotty calcification, low-attenuation fatty core, positive remodeling, and thin fibrous cap. We will also review several studies that assessed features of a vulnerable plaque on non-invasive imaging and evaluated them as risk predictors of future acute coronary events. Summary: Multiple recent studies suggested that coronary computed tomography angiography can accurately identify high-risk features of plaque that will predict future events.
KW - Acute coronary syndrome
KW - Coronary computed tomography
KW - Plaque
UR - http://www.scopus.com/inward/record.url?scp=85089243446&partnerID=8YFLogxK
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U2 - 10.1007/s11883-020-00879-z
DO - 10.1007/s11883-020-00879-z
M3 - Review article
C2 - 32772222
AN - SCOPUS:85089243446
VL - 22
JO - Current Atherosclerosis Reports
JF - Current Atherosclerosis Reports
SN - 1523-3804
IS - 10
M1 - 58
ER -