Ispol'zovanie immunogistokhimicheskogo metoda dlia vyiavleniia N7-metilguanina v kletkakh cheloveka.

Translated title of the contribution: The use of an immunohistochemical method for detecting N7-methylguanine in human cells

Andrei M Mikheev

Research output: Contribution to journalArticle

Abstract

An immunohistochemical method, followed by silvering (Ag-treatment) of the final product of peroxidase reaction for N7-methylguanine detection, was first employed for human cells treated in vitro with N-methylnitrosourea. This method appeared to be highly specific and sensitive, compared to the routine immunohistochemical technique. Evidence has been provided on the application of Ag-treatment for detecting N7-methylguanine in the esophagus epithelium of patients with a high risk of cancer with this particular locality.

Translated title of the contributionThe use of an immunohistochemical method for detecting N7-methylguanine in human cells
Original languageRussian
Pages (from-to)57-61
Number of pages5
JournalTsitologiya
Volume34
Issue number3
StatePublished - Jan 1 1992

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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