The syndrome of inappropriate secretion of antidiuretic hormone in children with bacterial meningitis

Sheldon L. Kaplan, Ralph D. Feigin

Research output: Contribution to journalArticle

60 Scopus citations

Abstract

Plasma concentrations of arginine vasopressin were determined by radioimmunoassay in 13 normal children, 21 patients with febrile illnesses (not bacterial meningitis), and 17 patients with bacterial meningitis. The mean ±1 SD concentrations of AVP in the normal children and patients with various febrile illnesses were 0.7±0.6 and 1.0±1.2 μU/ml, respectively. The mean ±1 SD concentration of AVP in patients with bacterial meningitis was 3.3±2.3 μU/ml. The concentrations of AVP in the patients with bacterial meningitis were significantly greater (P<0.001) than those noted in the normal children or children with other febrile diseases.

Original languageEnglish (US)
Pages (from-to)758-761
Number of pages4
JournalThe Journal of Pediatrics
Volume92
Issue number5
DOIs
StatePublished - May 1978

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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