The Role of Toluidine Blue in Mohs Micrographic Surgery: A Systematic Review

Tyler Long; Austin Dunn; Dane Hill; Leonard H. Goldberg; Russel Akin

doi:10.12788/cutis.0915

The Role of Toluidine Blue in Mohs Micrographic Surgery: A Systematic Review

Tyler Long, Austin Dunn, Dane Hill, Leonard H. Goldberg, Russel Akin

Research output: Contribution to journal › Article › peer-review

Abstract

Toluidine blue (TB) is a metachromatic dye used as a stain in frozen sections in Mohs micrographic surgery (MMS). The current literature on the use of TB is sparse and generally qualitative in nature. The aim of this systematic review was to summarize and evaluate the existing literature analyzing TB use in MMS. The PubMed and Cochrane databases were searched for relevant studies published before December 1, 2019. Studies that analyzed the use of TB in frozen sections applicable to MMS were included. A total of 25 articles were reviewed, of which 12 fit the inclusion criteria. Our analysis showed that TB may play an important role in the successful diagnosis and treatment of particular cutaneous tumors.

Original language	English (US)
Pages (from-to)	E6-E11
Journal	Cutis
Volume	112
Issue number	6
DOIs	https://doi.org/10.12788/cutis.0915
State	Published - Dec 2023

ASJC Scopus subject areas

Dermatology

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10.12788/cutis.0915

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title = "The Role of Toluidine Blue in Mohs Micrographic Surgery: A Systematic Review",

abstract = "Toluidine blue (TB) is a metachromatic dye used as a stain in frozen sections in Mohs micrographic surgery (MMS). The current literature on the use of TB is sparse and generally qualitative in nature. The aim of this systematic review was to summarize and evaluate the existing literature analyzing TB use in MMS. The PubMed and Cochrane databases were searched for relevant studies published before December 1, 2019. Studies that analyzed the use of TB in frozen sections applicable to MMS were included. A total of 25 articles were reviewed, of which 12 fit the inclusion criteria. Our analysis showed that TB may play an important role in the successful diagnosis and treatment of particular cutaneous tumors.",

author = "Tyler Long and Austin Dunn and Dane Hill and Goldberg, {Leonard H.} and Russel Akin",

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AU - Dunn, Austin

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AU - Akin, Russel

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PY - 2023/12

Y1 - 2023/12

N2 - Toluidine blue (TB) is a metachromatic dye used as a stain in frozen sections in Mohs micrographic surgery (MMS). The current literature on the use of TB is sparse and generally qualitative in nature. The aim of this systematic review was to summarize and evaluate the existing literature analyzing TB use in MMS. The PubMed and Cochrane databases were searched for relevant studies published before December 1, 2019. Studies that analyzed the use of TB in frozen sections applicable to MMS were included. A total of 25 articles were reviewed, of which 12 fit the inclusion criteria. Our analysis showed that TB may play an important role in the successful diagnosis and treatment of particular cutaneous tumors.

AB - Toluidine blue (TB) is a metachromatic dye used as a stain in frozen sections in Mohs micrographic surgery (MMS). The current literature on the use of TB is sparse and generally qualitative in nature. The aim of this systematic review was to summarize and evaluate the existing literature analyzing TB use in MMS. The PubMed and Cochrane databases were searched for relevant studies published before December 1, 2019. Studies that analyzed the use of TB in frozen sections applicable to MMS were included. A total of 25 articles were reviewed, of which 12 fit the inclusion criteria. Our analysis showed that TB may play an important role in the successful diagnosis and treatment of particular cutaneous tumors.

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The Role of Toluidine Blue in Mohs Micrographic Surgery: A Systematic Review

Abstract

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