TY - JOUR
T1 - The role of inflammation in the pathogenesis of heart failure
AU - Lisman, Kevin A.
AU - Stetson, Sonny J.
AU - Koerner, Michael M.
AU - Farmer, John A.
AU - Torre, Guillermo
PY - 2002/12/1
Y1 - 2002/12/1
N2 - Heart failure is not a simple defect in the pumping function of cardiac muscle, but rather a complex systemic inflammatory disease affecting many organ systems. Recognition of this fact has led to new therapeutic interventions such as angiotensin-converting enzyme inhibitors and b-blockers, which have a significant impact on the quality of life and survival of patients with heart failure. During the course of heart failure, the steps involved in the activation of inflammation are now better understood. As a result, new therapies will develop that block, modify, or prevent these inflammatory changes, and supplement our armamentarium for providing better and longer lives for patients.
AB - Heart failure is not a simple defect in the pumping function of cardiac muscle, but rather a complex systemic inflammatory disease affecting many organ systems. Recognition of this fact has led to new therapeutic interventions such as angiotensin-converting enzyme inhibitors and b-blockers, which have a significant impact on the quality of life and survival of patients with heart failure. During the course of heart failure, the steps involved in the activation of inflammation are now better understood. As a result, new therapies will develop that block, modify, or prevent these inflammatory changes, and supplement our armamentarium for providing better and longer lives for patients.
UR - https://www.scopus.com/pages/publications/0036581229
UR - https://www.scopus.com/inward/citedby.url?scp=0036581229&partnerID=8YFLogxK
U2 - 10.1007/s11886-002-0051-3
DO - 10.1007/s11886-002-0051-3
M3 - Article
C2 - 11960588
AN - SCOPUS:0036581229
SN - 1523-3782
VL - 4
SP - 200
EP - 205
JO - Current Cardiology Reports
JF - Current Cardiology Reports
IS - 3
ER -