TY - JOUR
T1 - The Role of Escherichia coli dnaG Function in Coliphage M 13 DNA Synthesis
AU - DASGUPTA, Santanu
AU - MITRA, Saukar
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1976/8
Y1 - 1976/8
N2 - Examination of the role of Escherichia coli dnaG function in different stages of M13 phage DNA synthesis by ultracentrifugal analysis of intracellular phage DNA in a thermosensitive dnaG mutant shows that: the formation of parental double strand replicative form DNA (rfDNA) from the infecting virus is independent of dnaG function; the synthesis of progeny rfDNA requires dnaG product; after a pool of rfDNA is made up, dnaG function is not required for the progeny single strand DNA (ssDNA) synthesis. The ssDNAs produced under nonpermissive condition are mostly circular and biologically functional.
AB - Examination of the role of Escherichia coli dnaG function in different stages of M13 phage DNA synthesis by ultracentrifugal analysis of intracellular phage DNA in a thermosensitive dnaG mutant shows that: the formation of parental double strand replicative form DNA (rfDNA) from the infecting virus is independent of dnaG function; the synthesis of progeny rfDNA requires dnaG product; after a pool of rfDNA is made up, dnaG function is not required for the progeny single strand DNA (ssDNA) synthesis. The ssDNAs produced under nonpermissive condition are mostly circular and biologically functional.
UR - http://www.scopus.com/inward/record.url?scp=0017087547&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017087547&partnerID=8YFLogxK
U2 - 10.1111/j.1432-1033.1976.tb10630.x
DO - 10.1111/j.1432-1033.1976.tb10630.x
M3 - Article
C2 - 786625
AN - SCOPUS:0017087547
VL - 67
SP - 47
EP - 51
JO - European Journal of Biochemistry
JF - European Journal of Biochemistry
SN - 0014-2956
IS - 1
ER -