The role of elective neck dissection in patients undergoing salvage laryngectomy

Moran Amit, Ohad Hilly, Leonor Leider-Trejo, Aharon Popovtzer, Orit Gutfeld, Jacob Shvero, Dan M. Fliss, Jacob T. Cohen, Gideon Bachar, Ziv Gil

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


Background. We investigated the risk of neck metastases in patients undergoing salvage total laryngectomy in association with previous radiotherapy. Methods. The medical records of 42 patients (51 neck specimens) with clinical N0 classification who underwent salvage total laryngectomy in 2 cancer centers were reviewed. Fourteen patients had previous radiotherapy to the central neck and 28 to the central and lateral neck. Results. Staging before salvage total laryngectomy was similar in both groups. The risk of neck metastases in the central and central/lateral radiation groups was 12% and 18%, respectively (p =.69). Subgroup analysis revealed that 4 of 8 patients initially presenting with clinically N+ had neck metastases before surgery, versus 2 of 26 for those with clinically N0 (p =.015; relative risk [RR] = 4.67). The risk or metastases in the contralateral neck was 0 of 9. Conclusion. The risk of neck metastases in patients who undergo either central or central/lateral neck radiotherapy is similar. Elective neck dissection seems appropriate in patients undergoing SLR.

Original languageEnglish (US)
Pages (from-to)1392-1396
Number of pages5
JournalHead and Neck
Issue number10
StatePublished - Oct 2013


  • cancer
  • Larynx
  • lymph node metastases
  • neck dissection
  • radiotherapy

ASJC Scopus subject areas

  • Otorhinolaryngology


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