The role of DNA polymerase I-associated 5′-exonuclease in replication of coliphage M13 replicative-form DNA

Santanu Dasgupta, Sankar Mitra

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

The conversion of both parental- and progeny-nascent open circular M13 RF DNA into covalently closed RF I is drastically reduced in an E. coli mutant deficient in the 5′ → 3′ exonuclease associated with DNA polymerase I. The nascent progeny RF DNA also contains a significant proportion of fragments of smaller than unit length.

Original languageEnglish (US)
Pages (from-to)1108-1113
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume78
Issue number3
DOIs
StatePublished - Oct 10 1977

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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