The Role of Cardiac PET in Diagnosis and Prognosis of Ischemic Heart Disease: Optimal Modality Across Different Patient Populations

Malek Nayfeh, Ahmed Ibrahim Ahmed, Jean Michel Saad, Fares Alahdab, Mouaz Al-Mallah

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

Purpose of Review: Despite single-photon emission computerized tomography (SPECT) being the most used nuclear imaging technique for diagnosis of coronary artery disease (CAD), many now consider positron emission tomography (PET) as a superior modality. This review will focus on the advances of cardiac PET in recent years and its advantages compared to SPECT in diagnosis and prognosis of CAD. Recent Findings: PET’s higher resolution and enhanced diagnostic accuracy, as well as lower radiation exposure, all help explain the rationale for its wider spread and use. PET also allows for measurement of myocardial blood flow (MBF) and myocardial flow reserve (MFR), which aids in several different clinical scenarios, such as diagnosing multivessel disease or identifying non-responders. PET has also been shown to be useful in diagnosing CAD in various specific populations, such as patients with prior COVID-19 infection, cardiac transplant, and other comorbidities.

Original languageEnglish (US)
Pages (from-to)351-357
Number of pages7
JournalCurrent Atherosclerosis Reports
Volume25
Issue number7
DOIs
StatePublished - Jul 2023

Keywords

  • Ischemia
  • Myocardial flow reserve
  • Myocardial perfusion
  • Positron emission tomography
  • Myocardial Perfusion Imaging/methods
  • Prognosis
  • COVID-19 Testing
  • Humans
  • COVID-19
  • Myocardial Ischemia/diagnostic imaging
  • Coronary Artery Disease/diagnostic imaging
  • Fractional Flow Reserve, Myocardial/physiology
  • Positron-Emission Tomography/methods
  • Coronary Angiography/methods

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint

Dive into the research topics of 'The Role of Cardiac PET in Diagnosis and Prognosis of Ischemic Heart Disease: Optimal Modality Across Different Patient Populations'. Together they form a unique fingerprint.

Cite this