The results of radiation therapy of patients with pure seminoma of the testis

Between 1967 and 1985, 75 patients with pure seminoma of the testis were treated with radiation therapy for periaortic and ipsilateral iliac areas following orchiectomy at the Department of Radiology, Osaka University Hospital. All patients except three were followed at least 2 years. Concerning patients who received 28-30 Gy, all of 48 patients with N0 disease were controlled and alive 2 to 20 years after radiation therapy. All of four patients with N1 disease were controlled and alive 6 to 16 years after radiation therapy. Six of 7 patients with N2 disease were controlled and alive 6 to 19 years after radiation therapy but one patient with T1N2 disease who received 30 Gy to periaortic and ipsilateral iliac areas had recurrence in a paraaortic lymph node 11 months after radiation therapy. As for patients with N3 disease two patients were controlled after 38 Gy and 48 Gy, respectively. No complication was observed after radiation therapy. No sterility seemed to be induced by irradiation to periaortic and ipsilateral iliac areas. It may be concluded that dose of 30 Gy to periaortic and ipsilateral iliac areas is recommended for patients with N0 disease. However, for patients with N1 or N2 disease higher dose of 35 Gy or more is recommended.