The requirement for lipid fluidity in the formation and structure of lipoproteins: Thermotropic analysis of apolipoprotein-alanine binding to dimyristoyl phosphatidylcholine

Henry J. Pownall; J. D. Morrisett; J. T. Sparrow; Antonio Gotto

doi:10.1016/0006-291X(74)90308-8

The requirement for lipid fluidity in the formation and structure of lipoproteins: Thermotropic analysis of apolipoprotein-alanine binding to dimyristoyl phosphatidylcholine

Henry J. Pownall, J. D. Morrisett, J. T. Sparrow, Antonio Gotto

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

By circular dichroic, fluorescence and ultracentrifugal methods, it is shown that apoLP-alanine binds to dimyristoyl phosphatidylcholine in its liquid crystalline state more efficiently than its gel state.

Original language	English (US)
Pages (from-to)	779-786
Number of pages	8
Journal	Biochemical and Biophysical Research Communications
Volume	60
Issue number	2
DOIs	https://doi.org/10.1016/0006-291X(74)90308-8
State	Published - Sep 23 1974

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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10.1016/0006-291X(74)90308-8

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The requirement for lipid fluidity in the formation and structure of lipoproteins: Thermotropic analysis of apolipoprotein-alanine binding to dimyristoyl phosphatidylcholine. / Pownall, Henry J.; Morrisett, J. D.; Sparrow, J. T. et al.
In: Biochemical and Biophysical Research Communications, Vol. 60, No. 2, 23.09.1974, p. 779-786.

Research output: Contribution to journal › Article › peer-review

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abstract = "By circular dichroic, fluorescence and ultracentrifugal methods, it is shown that apoLP-alanine binds to dimyristoyl phosphatidylcholine in its liquid crystalline state more efficiently than its gel state.",

author = "Pownall, \{Henry J.\} and Morrisett, \{J. D.\} and Sparrow, \{J. T.\} and Antonio Gotto",

note = "Funding Information: *This work was supported in paxt by Health, Education, Grant HL-14194, by a grant from the John A. Hartford NIH General Clinical Research Center Grant RR-00350. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

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AU - Sparrow, J. T.

AU - Gotto, Antonio

N1 - Funding Information: *This work was supported in paxt by Health, Education, Grant HL-14194, by a grant from the John A. Hartford NIH General Clinical Research Center Grant RR-00350. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

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The requirement for lipid fluidity in the formation and structure of lipoproteins: Thermotropic analysis of apolipoprotein-alanine binding to dimyristoyl phosphatidylcholine

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