Abstract
The smooth muscle contractile properties of 100 human saphenous veins derived from healthy tissue and organ donors were investigated. No significant changes in the contractile responses of saphenous veins to potassium chloride, serotonin, and norepinephrine were associated with age. In contrast, comparison of contractile responses between males and females demonstrated significantly less response to potassium chloride in female veins (P<0.05). Female contractile responses to serotonin (P=0.74) and norepinephrine (P=0.29) did not differ significantly when compared with male responses. These observations support the conclusion that gender may be an important variable in saphenous vein biology.
Original language | English (US) |
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Pages (from-to) | 15-21 |
Number of pages | 7 |
Journal | Vascular and Endovascular Surgery |
Volume | 29 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1995 |
ASJC Scopus subject areas
- Surgery
- Cardiology and Cardiovascular Medicine