TY - JOUR
T1 - The proximal probe in esophageal pH monitoring
T2 - Development of a normative database
AU - Vincent, Daniel A.
AU - Garrett, J. David
AU - Radionoff, Sharon L.
AU - Reussner, Lee A.
AU - Stasney, C. Richard
N1 - Funding Information:
Acknowledgment: The authors wish to thank Margarita Rodriguez for her help in coordinating patient enrollment and testing, and David Norton, RCP for assistance with pH probe testing. This study was supported in part by a research grant from Medtronic Functional Diagnostics, Shoreview, Minnesota, and also by the Texas Voice Institute at The Methodist Hospital, Texas Medical Center, Houston, Texas.
PY - 2000
Y1 - 2000
N2 - Healthy volunteers without symptoms of either gastroesophageal reflux or laryngopharyngeal reflux and without abnormalities on laryngologic examination were recruited for esophageal pH monitoring. Thirty subjects underwent ambulatory 24-hour double-channel pH probe monitoring to establish normative data for the upper probe, which was positioned just above the upper esophageal sphincter. Data were analyzed excluding meal periods plus 2 minutes of postprandial time. The mean, standard deviation, median, and 95th percentile were calculated for various reflux parameters for the following intervals: total study duration, upright time, supine time, and postprandial time. Normal subjects display physiologic reflux above the upper esophageal sphincter (median one event, 95th percentile 6.9 events), and 80.4% of these events occur in the upright position. The reflux area index (RAI) appears to be the most useful parameter to measure laryngopharyngeal reflux severity.
AB - Healthy volunteers without symptoms of either gastroesophageal reflux or laryngopharyngeal reflux and without abnormalities on laryngologic examination were recruited for esophageal pH monitoring. Thirty subjects underwent ambulatory 24-hour double-channel pH probe monitoring to establish normative data for the upper probe, which was positioned just above the upper esophageal sphincter. Data were analyzed excluding meal periods plus 2 minutes of postprandial time. The mean, standard deviation, median, and 95th percentile were calculated for various reflux parameters for the following intervals: total study duration, upright time, supine time, and postprandial time. Normal subjects display physiologic reflux above the upper esophageal sphincter (median one event, 95th percentile 6.9 events), and 80.4% of these events occur in the upright position. The reflux area index (RAI) appears to be the most useful parameter to measure laryngopharyngeal reflux severity.
KW - Laryngopharyngeal reflux disease
KW - Normative database
KW - PH probe protocol
KW - Proximal esophageal reflux
UR - https://www.scopus.com/pages/publications/12944254456
UR - https://www.scopus.com/inward/citedby.url?scp=12944254456&partnerID=8YFLogxK
U2 - 10.1016/S0892-1997(00)80033-8
DO - 10.1016/S0892-1997(00)80033-8
M3 - Article
C2 - 10875577
AN - SCOPUS:12944254456
SN - 0892-1997
VL - 14
SP - 247
EP - 254
JO - Journal of Voice
JF - Journal of Voice
IS - 2
ER -