Abstract
Healthy volunteers without symptoms of either gastroesophageal reflux or laryngopharyngeal reflux and without abnormalities on laryngologic examination were recruited for esophageal pH monitoring. Thirty subjects underwent ambulatory 24-hour double-channel pH probe monitoring to establish normative data for the upper probe, which was positioned just above the upper esophageal sphincter. Data were analyzed excluding meal periods plus 2 minutes of postprandial time. The mean, standard deviation, median, and 95th percentile were calculated for various reflux parameters for the following intervals: total study duration, upright time, supine time, and postprandial time. Normal subjects display physiologic reflux above the upper esophageal sphincter (median one event, 95th percentile 6.9 events), and 80.4% of these events occur in the upright position. The reflux area index (RAI) appears to be the most useful parameter to measure laryngopharyngeal reflux severity.
Original language | English (US) |
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Pages (from-to) | 247-254 |
Number of pages | 8 |
Journal | Journal of Voice |
Volume | 14 |
Issue number | 2 |
DOIs | |
State | Published - 2000 |
Keywords
- Laryngopharyngeal reflux disease
- Normative database
- PH probe protocol
- Proximal esophageal reflux
ASJC Scopus subject areas
- Otorhinolaryngology