TY - JOUR
T1 - The promise of comparative genomics in mammals
AU - O'Brien, Stephen J.
AU - Menotti-Raymond, Marilyn
AU - Murphy, William J.
AU - Nash, William G.
AU - Wienberg, Johannes
AU - Stanyon, Roscoe
AU - Copeland, Neal G.
AU - Jenkins, Nancy A.
AU - Womack, James E.
AU - Marshall Graves, Jennifer A.
PY - 1999/10/15
Y1 - 1999/10/15
N2 - Dense genetic maps of human, mouse, and rat genomes that are based on coding genes and on microsatellite and single-nucleotide polymorphism markers have been complemented by precise gene homolog alignment with moderate- resolution maps of livestock, companion animals, and additional mammal species. Comparative genetic assessment expands the utility of these maps in gene discovery, in functional genomics, and in tracking the evolutionary forces that sculpted the genome organization of modern mammalian species.
AB - Dense genetic maps of human, mouse, and rat genomes that are based on coding genes and on microsatellite and single-nucleotide polymorphism markers have been complemented by precise gene homolog alignment with moderate- resolution maps of livestock, companion animals, and additional mammal species. Comparative genetic assessment expands the utility of these maps in gene discovery, in functional genomics, and in tracking the evolutionary forces that sculpted the genome organization of modern mammalian species.
UR - http://www.scopus.com/inward/record.url?scp=0033569387&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033569387&partnerID=8YFLogxK
U2 - 10.1126/science.286.5439.458
DO - 10.1126/science.286.5439.458
M3 - Review article
C2 - 10521336
AN - SCOPUS:0033569387
VL - 286
SP - 458
EP - 463
JO - Science (New York, N.Y.)
JF - Science (New York, N.Y.)
SN - 0036-8075
IS - 5439
ER -