The probiotic Bifidobacterium in the management of Coronavirus: A theoretical basis

Hüseyin S. Bozkurt, Eamonn M.M. Quigley

Research output: Contribution to journalEditorialpeer-review

35 Scopus citations


COVID-19 is a viral pandemic that primarily manifests with respiratory distress but may also lead to symptoms and signs associated with the gastrointestinal tract. It is characteristically associated with a hyper-immune response, also referred to as a ‘cytokine storm’. Probiotics are living microorganisms that have been shown to have positive effects on immune response in man with some bacteria; some strains of Bifidobacteria, for example, possess especially potent immune modulating effects. These bacteria have the potential to ameliorate the ‘cytokine storm’ through a differential effect on pro- and anti-inflammatory cytokines. In the management of COVID-19 and other coronovirus-mediated illnesses, probiotic bacteria also have the potential to enhance vaccine efficacy.

Original languageEnglish (US)
JournalInternational Journal of Immunopathology and Pharmacology
StatePublished - Oct 27 2020


  • bifidobacterium
  • covid-19
  • probiotic
  • Bifidobacterium
  • Pandemics
  • Probiotics/therapeutic use
  • Pneumonia, Viral/immunology
  • Humans
  • Gastrointestinal Microbiome
  • Coronavirus Infections/immunology

ASJC Scopus subject areas

  • Immunology and Allergy
  • Pharmacology
  • Immunology


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