The potential of polyester fibrous leaflets for transcatheter heart valves

Antoine Vaesken, Nabil Chakfe, Atieh Yousefi Koupaei, Lakshmi Prasad Dasi, Frédéric Heim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Statement of Purpose: Transcatheter aortic valve replacement (TAVR) has become a popular alternative technique to surgical valve replacement for critical patients and is expected to be extended to less critical patients in a close future. However, with 10 years follow up, little is known about the long-term durability of the biological tissue currently used in the procedure. Moreover, the high cost of tissue harvesting and chemical treatment procedures favor the development of alternative synthetic valve leaflet materials. Textile polyester is one such material which provides outstanding folding and strength properties combined with proven biocompatibility, and could therefore be considered as a candidate to replace the biological valve leaflets in TAVR procedures.. Methods: Fabric valves were obtained from tubular woven polyester fibers (PET) membranes characterized by various textile constructions. The design of the valves was obtained with a heat based shaping process and from the geometry of the mold used to shape the cusps. The fabric valves were assembled with commercially available biological valve rings from which the biological tissue had been removed.

Original languageEnglish (US)
Title of host publicationSociety for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publicationThe Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
PublisherSociety for Biomaterials
Number of pages1
ISBN (Electronic)9781510883901
StatePublished - 2019
Event42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States
Duration: Apr 3 2019Apr 6 2019

Publication series

NameTransactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume40
ISSN (Print)1526-7547

Other

Other42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
CountryUnited States
CitySeattle
Period4/3/194/6/19

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Biotechnology
  • Biomaterials
  • Materials Chemistry

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