TY - JOUR
T1 - The neuroepidemiology of tropical spastic paraparesis
AU - Román, Gustavo C.
PY - 1988
Y1 - 1988
N2 - Recent neuroepidemiological studies of endemic tropical spastic paraparesis (TSP) have confirmed the existence of high-prevalence foci in several tropical islands, including Jamaica and Martinique in the Caribbean, Tumaco off the Pacific coast of Colombia, and the Seychelles in the Indian Ocean. There is a net preponderance of TSP in persons of Black African ancestry, although Caucasian, Hindu, Amerindian, and Orientals have been affected. The epidemiological, clinical, laboratory, and neuropathological features of TSP are reviewed here, as well as the evidence in favor of its retroviral origin.
AB - Recent neuroepidemiological studies of endemic tropical spastic paraparesis (TSP) have confirmed the existence of high-prevalence foci in several tropical islands, including Jamaica and Martinique in the Caribbean, Tumaco off the Pacific coast of Colombia, and the Seychelles in the Indian Ocean. There is a net preponderance of TSP in persons of Black African ancestry, although Caucasian, Hindu, Amerindian, and Orientals have been affected. The epidemiological, clinical, laboratory, and neuropathological features of TSP are reviewed here, as well as the evidence in favor of its retroviral origin.
UR - http://www.scopus.com/inward/record.url?scp=0023806011&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023806011&partnerID=8YFLogxK
U2 - 10.1002/ana.410230728
DO - 10.1002/ana.410230728
M3 - Article
C2 - 2894800
AN - SCOPUS:0023806011
SN - 0364-5134
VL - 23
SP - S113-S120
JO - Annals of Neurology
JF - Annals of Neurology
IS - 1 S
ER -