The neurobehavioural consequences of St. Louis encephalitis infection

Kevin W. Greve, Rebecca J. Houston, Donald Adams, Matthew S. Stanford, Kevin J. Bianchini, Annemarie Clancy, Frank J. Rabito

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Background: St. Louis encephalitis (SLE) is a relatively common cause of neurological illness, yet little is known about its cognitive and psychosocial consequences. Purpose: To describe the cognitive, emotional, psychophysiological, and psychosocial consequences of SLE infection. Method: A comprehensive neuropsychological and psychophysiological evaluation of a high functioning woman 6 weeks and 1 year after acute SLE infection is presented. The focus and course of rehabilitation is also examined. Results: The primary cognitive consequences of SLE infection involved attention, working memory, speed of processing, and cognitive efficiency. Depression was also observed. Psychometric testing suggested that these deficits largely resolved after 1 year. Conclusion: SLE produces neurocognitive deficits which are reflected in both psychometric and psychophysiologic measures and functional status. Psychometric and vocational improvement were observed over 1 year. However, the normal vocational return came at a significant psychosocial cost. This case emphasizes the importance of a comprehensive neuropsychological evaluation and illustrates the importance of an integrated rehabilitation programme.

Original languageEnglish (US)
Pages (from-to)917-927
Number of pages11
JournalBrain Injury
Issue number10
StatePublished - Oct 1 2002

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Developmental and Educational Psychology
  • Clinical Neurology


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