The leukemia inhibitory factor receptor (lifr) gene is located within a cluster of cytokine receptor loci on mouse chromosome 15 and human chromosome 5p12-p13

D. P. Gearing; T. Druck; K. Huebner; J. Overhauser; D. J. Gilbert; N. G. Copeland; N. A. Jenkins

doi:10.1006/geno.1993.1441

The leukemia inhibitory factor receptor (lifr) gene is located within a cluster of cytokine receptor loci on mouse chromosome 15 and human chromosome 5p12-p13

D. P. Gearing, T. Druck, K. Huebner, J. Overhauser, D. J. Gilbert, N. G. Copeland, N. A. Jenkins

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Abstract

The leukemia inhibitory factor receptor (LIFR) gene was localized to human chromosome 5p12-p13 by somatic cell hybrid analysis. Interspecific backcross analysis revealed that the murine locus was on chromosome 15 in a region of homology with human chromosome 5p. In both human and mouse genomes, the LIFR locus was linked to the genes encoding the receptors for interleukin-7, prolactin, and growth hormone.

Original language	English (US)
Pages (from-to)	148-150
Number of pages	3
Journal	Genomics
Volume	18
Issue number	1
DOIs	https://doi.org/10.1006/geno.1993.1441
State	Published - Oct 1993

ASJC Scopus subject areas

Genetics

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abstract = "The leukemia inhibitory factor receptor (LIFR) gene was localized to human chromosome 5p12-p13 by somatic cell hybrid analysis. Interspecific backcross analysis revealed that the murine locus was on chromosome 15 in a region of homology with human chromosome 5p. In both human and mouse genomes, the LIFR locus was linked to the genes encoding the receptors for interleukin-7, prolactin, and growth hormone.",

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AU - Gearing, D. P.

AU - Druck, T.

AU - Huebner, K.

AU - Overhauser, J.

AU - Gilbert, D. J.

AU - Copeland, N. G.

AU - Jenkins, N. A.

PY - 1993/10

Y1 - 1993/10

N2 - The leukemia inhibitory factor receptor (LIFR) gene was localized to human chromosome 5p12-p13 by somatic cell hybrid analysis. Interspecific backcross analysis revealed that the murine locus was on chromosome 15 in a region of homology with human chromosome 5p. In both human and mouse genomes, the LIFR locus was linked to the genes encoding the receptors for interleukin-7, prolactin, and growth hormone.

AB - The leukemia inhibitory factor receptor (LIFR) gene was localized to human chromosome 5p12-p13 by somatic cell hybrid analysis. Interspecific backcross analysis revealed that the murine locus was on chromosome 15 in a region of homology with human chromosome 5p. In both human and mouse genomes, the LIFR locus was linked to the genes encoding the receptors for interleukin-7, prolactin, and growth hormone.

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The leukemia inhibitory factor receptor (lifr) gene is located within a cluster of cytokine receptor loci on mouse chromosome 15 and human chromosome 5p12-p13

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