The Inflammatory Cascade in Acute Pancreatitis: Relevance to Clinical Disease

Mohammed Elfar, Lillian Gaber, Omaima Sabek, Craig P. Fischer, A. Osama Gaber

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations

Abstract

Acute pancreatitis is an inflammatory condition that is initiated by the intra pancreatic activation of proteases. Pancreatic enzyme activation triggers a local and systemic inflammatory response that is associated with recruitment of inflammatory cells into the pancreas and a widespread up-regulation of inflammatory markers in distant tissues.

Original languageEnglish (US)
Pages (from-to)1325-1340
Number of pages16
JournalSurgical Clinics of North America
Volume87
Issue number6
DOIs
StatePublished - Dec 1 2007

ASJC Scopus subject areas

  • Surgery

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