Abstract
Thoracic aortic disease (TAD) poses substantial risks during pregnancy, particularly for women with genetic conditions such as Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome. This review examines the epidemiology, risk assessment, and management of TAD in pregnancy. Preconception counseling is vital considering the hereditary nature of TAD and potential pregnancy-related complications. Genetic testing and imaging surveillance aid in risk assessment. Medical management, including beta-blockade and strict blood pressure control, is essential throughout pregnancy. Surgical interventions may be necessary in certain cases. A multidisciplinary approach involving cardiologists, obstetricians, cardiac surgeons, anesthesiologists, and other specialists with expertise in cardio-obstetrics is essential for optimal outcomes. Patient education and shared decision-making play vital roles in navigating the complexities of TAD in pregnancy and improving maternal and neonatal outcomes.
Original language | English (US) |
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Pages (from-to) | 51-58 |
Number of pages | 8 |
Journal | Methodist DeBakey cardiovascular journal |
Volume | 20 |
Issue number | 2 |
DOIs | |
State | Published - 2024 |
Keywords
- aortopathy
- cardiovascular genetics
- Marfan
- pregnancy
- Risk Assessment
- Humans
- Loeys-Dietz Syndrome/complications
- Pregnancy
- Female
- Aorta
- Marfan Syndrome/diagnosis
- Infant, Newborn
- Aortic Diseases
ASJC Scopus subject areas
- Medicine(all)