The Impact of Pregnancy in Patients with Thoracic Aortic Disease: Epidemiology, Risk Assessment, and Management Considerations

Valeria E. Duarte, Jessica N. Richardson, Michael N. Singh

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Thoracic aortic disease (TAD) poses substantial risks during pregnancy, particularly for women with genetic conditions such as Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome. This review examines the epidemiology, risk assessment, and management of TAD in pregnancy. Preconception counseling is vital considering the hereditary nature of TAD and potential pregnancy-related complications. Genetic testing and imaging surveillance aid in risk assessment. Medical management, including beta-blockade and strict blood pressure control, is essential throughout pregnancy. Surgical interventions may be necessary in certain cases. A multidisciplinary approach involving cardiologists, obstetricians, cardiac surgeons, anesthesiologists, and other specialists with expertise in cardio-obstetrics is essential for optimal outcomes. Patient education and shared decision-making play vital roles in navigating the complexities of TAD in pregnancy and improving maternal and neonatal outcomes.

Original languageEnglish (US)
Pages (from-to)51-58
Number of pages8
JournalMethodist DeBakey cardiovascular journal
Volume20
Issue number2
DOIs
StatePublished - 2024

Keywords

  • aortopathy
  • cardiovascular genetics
  • Marfan
  • pregnancy
  • Risk Assessment
  • Humans
  • Loeys-Dietz Syndrome/complications
  • Pregnancy
  • Female
  • Aorta
  • Marfan Syndrome/diagnosis
  • Infant, Newborn
  • Aortic Diseases

ASJC Scopus subject areas

  • Medicine(all)

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