The identification of epimeric 5-androstene-3,16,17-triols in plasma from the umbilical cord and in meconium, faeces and urine from infants

C. H.L. Shackleton; Jan-Ake Gustafsson; J. Sjövall

doi:10.1016/S0039-128X(70)80009-5

The identification of epimeric 5-androstene-3,16,17-triols in plasma from the umbilical cord and in meconium, faeces and urine from infants

C. H.L. Shackleton, Jan-Ake Gustafsson, J. Sjövall

Houston Methodist

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Meconium, plasma from the umbilical cord, and urine from infants contained two androstenetriols which were identified by gas chromatography-mass spectrometry as 5-androstene-3β,16α,17β-triol and 5-androstene-3β,16β,17α-triol. Only in meconium was the latter steroid the predominant epimer. Faeces from infants 4-6 weeks of age also contained these isomers and in addition 5-androstene-3β,16α,17α-triol and 5-androstene-3β,16β,17β-triol were identified.

Original language	English (US)
Pages (from-to)	131-137
Number of pages	7
Journal	Steroids
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/S0039-128X(70)80009-5
State	Published - Jan 1 1970

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Endocrinology
Pharmacology
Clinical Biochemistry
Organic Chemistry

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title = "The identification of epimeric 5-androstene-3,16,17-triols in plasma from the umbilical cord and in meconium, faeces and urine from infants",

abstract = "Meconium, plasma from the umbilical cord, and urine from infants contained two androstenetriols which were identified by gas chromatography-mass spectrometry as 5-androstene-3β,16α,17β-triol and 5-androstene-3β,16β,17α-triol. Only in meconium was the latter steroid the predominant epimer. Faeces from infants 4-6 weeks of age also contained these isomers and in addition 5-androstene-3β,16α,17α-triol and 5-androstene-3β,16β,17β-triol were identified.",

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T1 - The identification of epimeric 5-androstene-3,16,17-triols in plasma from the umbilical cord and in meconium, faeces and urine from infants

AU - Shackleton, C. H.L.

AU - Gustafsson, Jan-Ake

AU - Sjövall, J.

PY - 1970/1/1

Y1 - 1970/1/1

N2 - Meconium, plasma from the umbilical cord, and urine from infants contained two androstenetriols which were identified by gas chromatography-mass spectrometry as 5-androstene-3β,16α,17β-triol and 5-androstene-3β,16β,17α-triol. Only in meconium was the latter steroid the predominant epimer. Faeces from infants 4-6 weeks of age also contained these isomers and in addition 5-androstene-3β,16α,17α-triol and 5-androstene-3β,16β,17β-triol were identified.

AB - Meconium, plasma from the umbilical cord, and urine from infants contained two androstenetriols which were identified by gas chromatography-mass spectrometry as 5-androstene-3β,16α,17β-triol and 5-androstene-3β,16β,17α-triol. Only in meconium was the latter steroid the predominant epimer. Faeces from infants 4-6 weeks of age also contained these isomers and in addition 5-androstene-3β,16α,17α-triol and 5-androstene-3β,16β,17β-triol were identified.

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The identification of epimeric 5-androstene-3,16,17-triols in plasma from the umbilical cord and in meconium, faeces and urine from infants

Abstract

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