The identification of epimeric 5-androstene-3,16,17-triols in plasma from the umbilical cord and in meconium, faeces and urine from infants

C. H.L. Shackleton, Jan-Ake Gustafsson, J. Sjövall

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Meconium, plasma from the umbilical cord, and urine from infants contained two androstenetriols which were identified by gas chromatography-mass spectrometry as 5-androstene-3β,16α,17β-triol and 5-androstene-3β,16β,17α-triol. Only in meconium was the latter steroid the predominant epimer. Faeces from infants 4-6 weeks of age also contained these isomers and in addition 5-androstene-3β,16α,17α-triol and 5-androstene-3β,16β,17β-triol were identified.

Original languageEnglish (US)
Pages (from-to)131-137
Number of pages7
JournalSteroids
Volume15
Issue number1
DOIs
StatePublished - Jan 1 1970

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Endocrinology
  • Pharmacology
  • Clinical Biochemistry
  • Organic Chemistry

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