La microbiota intestinal humana y el metabolismo corporal: Implicaciones con la obesidad y la diabetes

Translated title of the contribution: The human intestinal microbiota and body metabolism: Implications with obesity and diabetes

Sridevi Devaraj, Peera Hemarajata, James Versalovic

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Obesity, metabolic syndrome, and type 2 diabetes are major public health challenges. Recently, interest has surged regarding the possible role of the intestinal microbiota as potential novel contributors to the increased prevalence of these 3 disorders. Recent advances in microbial DNA sequencing technologies have resulted in the widespread application of whole-genome sequencing technologies for metagenomic DNA analysis of complex ecosystems such as the human gut. Current evidence suggests that the gut microbiota affect nutrient acquisition, energy harvest, and a myriad of host metabolic pathways. Advances in the Human Microbiome Project and human metagenomics research will lead the way toward a greater understanding of the importance and role of the gut microbiome in metabolic disorders such as obesity, metabolic syndrome, and diabetes.

Translated title of the contributionThe human intestinal microbiota and body metabolism: Implications with obesity and diabetes
Original languageSpanish
Pages (from-to)421-434
Number of pages14
JournalActa Bioquimica Clinica Latinoamericana
Volume47
Issue number2
StatePublished - Apr 1 2013

ASJC Scopus subject areas

  • Clinical Biochemistry

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