Obesity, metabolic syndrome, and type 2 diabetes are major public health challenges. Recently, interest has surged regarding the possible role of the intestinal microbiota as potential novel contributors to the increased prevalence of these 3 disorders. Recent advances in microbial DNA sequencing technologies have resulted in the widespread application of whole-genome sequencing technologies for metagenomic DNA analysis of complex ecosystems such as the human gut. Current evidence suggests that the gut microbiota affect nutrient acquisition, energy harvest, and a myriad of host metabolic pathways. Advances in the Human Microbiome Project and human metagenomics research will lead the way toward a greater understanding of the importance and role of the gut microbiome in metabolic disorders such as obesity, metabolic syndrome, and diabetes.
|Translated title of the contribution||The human intestinal microbiota and body metabolism: Implications with obesity and diabetes|
|Number of pages||14|
|Journal||Acta Bioquimica Clinica Latinoamericana|
|State||Published - Apr 1 2013|
ASJC Scopus subject areas
- Clinical Biochemistry