Gormonochuvstvitel'nost' perevivnoǐ adenokartsinomy tolstoǐ kishki.

Translated title of the contribution: The hormonal sensitivity of a transplantable adenocarcinoma of the large intestine

L. M. Bershteǐn, M. A. Zabezhinskiǐ, A. N. Stukov, V. N. Kalikhevich, Andrei M Mikheev

Research output: Contribution to journalArticle

Abstract

It was found that repeated transplantation of ACATOL strain cells resulted in a loss of their sensitivity to growth-stimulating effect of pentagastrin. The effect of gastrin receptor antagonist proglumide, on ACATOL cells growth was inconstant. ACATOL tumor was sensitive to VIP and glucagon in vitro (as shown by adenylate cyclase activity assay), that makes the model promising for selecting potent hormone drugs against colorectal cancer.

Translated title of the contributionThe hormonal sensitivity of a transplantable adenocarcinoma of the large intestine
Original languageRussian
Pages (from-to)62-64
Number of pages3
JournalEksperimentalnaa onkologia
Volume12
Issue number5
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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