The HOPES Registry – Houston Methodist Hospital Outcomes-based Prospective Endpoints in Stroke

Rajan Gadhia, David McCane, Jason Lee, Ken Chyuan Ling, Kevin Jiang, David Chiu

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Background: We present a single institution registry with the novel feature of 90-day outcome assessments on all hospitalized acute stroke patients, inclusive of every patient with a primary discharge diagnosis of transient ischemic attack (TIA), acute ischemic stroke (AIS), nontraumatic subarachnoid hemorrhage (SAH), and intracerebral hemorrhage (ICH). Methods: Patient data obtained in the HOPES registry include demographics, comorbid diagnoses, medications, health behaviors, laboratory values, imaging studies, vital signs, and outcome measures, most notably the modified Rankin Scale (mRS) at 90 days. Results: From May 2016 to December 31, 2017, 1607 patients were enrolled in the HOPES registry. 90-day outcome assessments were captured on 1555 patients (97%): 1096 AIS, 230 ICH, 110 SAH, and 119 TIA patients. Mortality rates and 90-day outcomes were most favorable for TIA patients. Mortality and 90-day disability scores were poorest for patients in the ICH group. Conclusions: The inclusion of 90-day outcomes data will allow HOPES to stand apart among stroke registries as a new standard for stroke outcomes research. The registry will provide the necessary comprehensive data that the field needs as we transition our focus of stroke research to poststroke recovery.

Original languageEnglish (US)
Pages (from-to)2973-2976
Number of pages4
JournalJournal of Stroke and Cerebrovascular Diseases
Issue number11
StatePublished - Nov 2018


  • Registry
  • modified Rankin scale score
  • outcomes
  • stroke

ASJC Scopus subject areas

  • Surgery
  • Rehabilitation
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine


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