The growth mechanism of apatite nanocrystals assisted by citrate: Relevance to bone biomineralization

Michele Iafisco; Gloria Belén Ramírez-Rodríguez; Yuriy Sakhno; Anna Tampieri; Gianmario Martra; Jaime Gómez-Morales; José Manuel Delgado-López

doi:10.1039/c4ce01415d

The growth mechanism of apatite nanocrystals assisted by citrate: Relevance to bone biomineralization

Michele Iafisco, Gloria Belén Ramírez-Rodríguez, Yuriy Sakhno, Anna Tampieri, Gianmario Martra, Jaime Gómez-Morales, José Manuel Delgado-López

Houston Methodist

Research output: Contribution to journal › Article › peer-review

68 Scopus citations

Abstract

Here we report that citrate plays a key dual role in the apatite crystallization: driving a growth pathway via an amorphous precursor and controlling the size of nanocrystals by the non-classical oriented aggregation mechanism. These results provide new insights into bone mineralization, where the role of citrate might be wider than has been thought to date.

Original language	English (US)
Pages (from-to)	507-511
Number of pages	5
Journal	CrystEngComm
Volume	17
Issue number	3
DOIs	https://doi.org/10.1039/c4ce01415d
State	Published - Jan 21 2015

ASJC Scopus subject areas

General Chemistry
General Materials Science
Condensed Matter Physics

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abstract = "Here we report that citrate plays a key dual role in the apatite crystallization: driving a growth pathway via an amorphous precursor and controlling the size of nanocrystals by the non-classical oriented aggregation mechanism. These results provide new insights into bone mineralization, where the role of citrate might be wider than has been thought to date.",

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T2 - Relevance to bone biomineralization

AU - Iafisco, Michele

AU - Ramírez-Rodríguez, Gloria Belén

AU - Sakhno, Yuriy

AU - Tampieri, Anna

AU - Martra, Gianmario

AU - Gómez-Morales, Jaime

AU - Delgado-López, José Manuel

PY - 2015/1/21

Y1 - 2015/1/21

N2 - Here we report that citrate plays a key dual role in the apatite crystallization: driving a growth pathway via an amorphous precursor and controlling the size of nanocrystals by the non-classical oriented aggregation mechanism. These results provide new insights into bone mineralization, where the role of citrate might be wider than has been thought to date.

AB - Here we report that citrate plays a key dual role in the apatite crystallization: driving a growth pathway via an amorphous precursor and controlling the size of nanocrystals by the non-classical oriented aggregation mechanism. These results provide new insights into bone mineralization, where the role of citrate might be wider than has been thought to date.

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U2 - 10.1039/c4ce01415d

DO - 10.1039/c4ce01415d

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JO - CrystEngComm

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The growth mechanism of apatite nanocrystals assisted by citrate: Relevance to bone biomineralization

Abstract

ASJC Scopus subject areas

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