The gene for murine CTP: Phosphocholine cytidylyltransferase (Ctpct) is located on mouse chromosome 16

Mark S. Rutherford, Charles O. Rock, Nancy A. Jenkins, Debra J. Gilbert, Teresa G. Tessner, Neal G. Copeland, Suzanne Jackowski

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

CTP:phosphocholine cytidylyltransferase is the rate-controlling enzyme in phosphatidylcholine biosynthesis and is essential for the survival of eukaryotic cells. The murine cDNA for the cytidylyltransferase was cloned and sequenced. A genomic clone was isolated and the chromosomal location of the Ctpct locus determined by Southern blot hybridization of DNAs from a panel of interspecific backcross progeny derived from matings of [(C57BL/6J × Mus spretus)F1 × C57BL/6J] mice. These data place the Ctpct gene on mouse chromosome 16 between the Smst and Stf-1 genes.

Original languageEnglish (US)
Pages (from-to)698-701
Number of pages4
JournalGenomics
Volume18
Issue number3
DOIs
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Genetics

Fingerprint Dive into the research topics of 'The gene for murine CTP: Phosphocholine cytidylyltransferase (Ctpct) is located on mouse chromosome 16'. Together they form a unique fingerprint.

Cite this