Modeling the tumor microenvironment as a biobarrier in cancer nanotherapeutics

Hermann B. Frieboes; Kenji Yokoi; Bhuvanesh Dave; Fazle Hussain; Biana Godin

doi:10.4032/9789814364423

Modeling the tumor microenvironment as a biobarrier in cancer nanotherapeutics

Hermann B. Frieboes, Kenji Yokoi, Bhuvanesh Dave, Fazle Hussain, Biana Godin

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

In this chapter, we review literature emphasizing the importance of bio-barriers in the tumor microenvironment and the main modeling approaches to predict transport of therapeutics across these obstacles. We further describe design considerations of the nanovectors to overcome the biobarriers.

Original language	English (US)
Title of host publication	Mass Transport of Nanocarriers
Publisher	Pan Stanford Publishing Pte. Ltd.
Pages	137-183
Number of pages	47
ISBN (Print)	9789814364416
DOIs	https://doi.org/10.4032/9789814364423
State	Published - Dec 31 2012

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Physics and Astronomy
General Medicine

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abstract = "In this chapter, we review literature emphasizing the importance of bio-barriers in the tumor microenvironment and the main modeling approaches to predict transport of therapeutics across these obstacles. We further describe design considerations of the nanovectors to overcome the biobarriers.",

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AU - Frieboes, Hermann B.

AU - Yokoi, Kenji

AU - Dave, Bhuvanesh

AU - Hussain, Fazle

AU - Godin, Biana

PY - 2012/12/31

Y1 - 2012/12/31

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M3 - Chapter

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BT - Mass Transport of Nanocarriers

PB - Pan Stanford Publishing Pte. Ltd.

ER -

Modeling the tumor microenvironment as a biobarrier in cancer nanotherapeutics

Abstract

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