Modeling the tumor microenvironment as a biobarrier in cancer nanotherapeutics

Hermann B. Frieboes, Kenji Yokoi, Bhuvanesh Dave, Fazle Hussain, Biana Godin

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


In this chapter, we review literature emphasizing the importance of bio-barriers in the tumor microenvironment and the main modeling approaches to predict transport of therapeutics across these obstacles. We further describe design considerations of the nanovectors to overcome the biobarriers.

Original languageEnglish (US)
Title of host publicationMass Transport of Nanocarriers
PublisherPan Stanford Publishing Pte. Ltd.
Number of pages47
ISBN (Print)9789814364416
StatePublished - Dec 31 2012

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Physics and Astronomy(all)
  • Medicine(all)


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