TY - JOUR
T1 - The Emerging Role of Nanotechnology in Cell and Organ Transplantation
AU - Tasciotti, Ennio
AU - Cabrera, Fernando J.
AU - Evangelopoulos, Michael
AU - Martinez, Jonathan O.
AU - Thekkedath, Usha R.
AU - Kloc Stepkowska, Malgorzata
AU - Ghobrial, Rafik M.
AU - Li, Xian Chang
AU - Grattoni, Alessandro
AU - Ferrari, Mauro
N1 - Funding Information:
Department of Defense grants W81XWH-09-1-0212 and W81XWH-12-1-0414, National Institutes of Health grants U54CA143837 and U54CA151668, the CPRIT grant RP121071 from the State of Texas, the Brown Foundation, The Cullen Trust for Health Care Foundation, The Hearst Foundation and the Ernest Cockrell, Jr. Presidential Distinguished Chair.
Publisher Copyright:
Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/6/2
Y1 - 2016/6/2
N2 - ABSTRACT: Transplantation is often the only choice many patients have when suffering from end-stage organ failure. Although the quality of life improves after transplantation, challenges, such as organ shortages, necessary immunosuppression with associated complications, and chronic graft rejection, limit its wide clinical application. Nanotechnology has emerged in the past 2 decades as a field with the potential to satisfy clinical needs in the area of targeted and sustained drug delivery, noninvasive imaging, and tissue engineering. In this article, we provide an overview of popular nanotechnologies and a summary of the current and potential uses of nanotechnology in cell and organ transplantation.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.
AB - ABSTRACT: Transplantation is often the only choice many patients have when suffering from end-stage organ failure. Although the quality of life improves after transplantation, challenges, such as organ shortages, necessary immunosuppression with associated complications, and chronic graft rejection, limit its wide clinical application. Nanotechnology has emerged in the past 2 decades as a field with the potential to satisfy clinical needs in the area of targeted and sustained drug delivery, noninvasive imaging, and tissue engineering. In this article, we provide an overview of popular nanotechnologies and a summary of the current and potential uses of nanotechnology in cell and organ transplantation.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.
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U2 - 10.1097/TP.0000000000001100
DO - 10.1097/TP.0000000000001100
M3 - Article
C2 - 27257995
AN - SCOPUS:84973348817
VL - 100
SP - 1629
EP - 1638
JO - Transplantation
JF - Transplantation
SN - 0041-1337
IS - 8
ER -