The cytogenetics and molecular genetics of lung cancer. Implications for pathologists.

Philip T. Cagle

Research output: Contribution to journalReview article

8 Scopus citations

Abstract

The interactions of cytogenetic and molecular genetic changes in the pathogenesis and progression of lung cancer are complex. To the practicing pathologist, certain of these changes may prove useful as diagnostic or prognostic markers and may help in selecting patients for particular types of therapy. Changes such as 3p14-23 deletions, c-myc amplification, and L-myc RFLPs have already been reported to predict aggressive behavior in lung cancer. Future studies will clarify the application of these changes to the clinical care and treatment of patients with carcinoma of the lung.

Original languageEnglish (US)
Pages (from-to)317-329
Number of pages13
JournalPathology Annual
Volume25 Pt 2
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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